Materiali Scientifici
2011 Watch: Landmark larynx transplant
In one of the most complex transplant surgeries ever performed, an international team of surgeons which included Professor Martin Birchall (UCL Ear Institute) has restored the voice of a US woman who had been unable to speak for more than a decade.
2011 Comunicato stampa 17/2/2011
Team of surgeons from B.V. Petrovsky Russian Research Centre of Surgery of the Russian Academy of Medical Sciences, lead by professor Vladimir Parshin, first time in Russia performed the transplantation of trachea without immunosuppression based on the regenerative medicine approach.
2011 Stem Cells and Cell Therapies in Lung Biology and Lung Diseases
Supported by the National Heart, Lung, and Blood Institute, Alpha-1 Foundation, American Thoracic Society, LAM Treatment Alliance Pulmonary Fibrosis Foundation, University of Vermont College of Medicine, Vermont Lung Center
2011 (Book Chapter) Trachea
Silvia Baiguera and Paolo Macchiarini 2011, Regenerative Medicine, Part 4, Pages 691-711
2011 Harvard Bioscience
PBS's Nova ScienceNow Features Harvard Bioscience Bioreactors for Lung and Airway Regeneration
2011 Regenerative Medicine
New 3D Bioreactor Systems
2011 Elenco articoli citati su PubMed
2011 Cutting Edge Laryngology
2010 Structural and morphologic evaluation of a novel detergent-enzymatic tissue-engineered tracheal tubular matrix.
Jungebluth P, Go T, Asnaghi A, Bellini S, Martorell J, Calore C, Urbani L, Ostertag H, Mantero S, Conconi MT, Macchiarini P. J Thorac Cardiovasc Surg. 2009 Sep;138(3):586-93; discussion 592-3. Epub 2009 Jul 14. PubMed PMID: 19698839.
2010 Both epithelial cells and mesenchymal stem cell–derived chondrocytes contribute to the survival of tissue-engineered airway transplants in pigs
Go T, Jungebluth P, Baiguero S, Asnaghi A, Martorell J, Ostertag H, Mantero S, Birchall M, Bader A, Macchiarini P. J Thorac Cardiovasc Surg. 2010 Feb;139(2):437-43. Epub 2009 Dec 7. PubMed PMID: 19995663.
2010 Oxygen mass transfer in a human tissue-engineered trachea
purchase Efrem Curcio (a), (b), Paolo Macchiarini (c) and Loredana De Bartolo (a),
a -Institute on Membrane Technology, National Research Council of Italy, ITM-CNR, c/o University of Calabria, Via P. Bucci cubo 17/C, I-87030 Rende (CS), Italy
b - Department of Chemical Engineering and Materials, University of Calabria, Via P. Bucci cubo 45/A, I-87030 Rende (CS), Italy
c - BIOAIR (Laboratory of Biomolecular and Bioengineering Airways), University Hospital Careggi, Florence, Via Olbiate 1, I-50141 Florence, Italy Received 27 January 2010; accepted 4 March 2010. Available online 8 April 2010.
2010 Translating tissue-engineered tracheal replacement from bench to bedside
Madhuri Kalathur, Silvia Baiguera and Paolo Macchiarini Cellular and Molecular Life Sciences Volume 67, Number 24, 4185-4196, DOI: 10.1007/s00018-010-0499-z
2010 Laryngeal transplantation in minipigs: vascular, myologic and functional outcomes.
Birchall MA, Kingham PJ, Murison PJ, Ayling SM, Burt R, Mitchard L, Jones A, Lear P, Stokes CR, Terenghi G, Bailey M, Macchiarini P. Eur Arch Otorhinolaryngol. 2011 Mar;268(3):405-14. Epub 2010 Sep 15. PubMed PMID: 20842506.
2010 Moving towards in situ tracheal regeneration: the bionic tissue engineered transplantation approach.
Bader, A. and Macchiarini, P. (2010), Journal of Cellular and Molecular Medicine, 14: 1877–1889. doi: 10.1111/j.1582-4934.2010.01073.x
2010 Harward Medical School - General Thoracic Surgery
2010 World first transplant in child
2009 Regenerative Medicine: a Forum for Clinical Need
Forum Report
2009 The first stem cell-based tissue-engineered organ replacement: implications for regenerative medicine and society
2009 Pratical Information - ANNEX 1
The Knowledge Triangle Shaping the Future of Europe
2009 First International Symposium
Translational Regenerative Medicine
2006 Lancet Oncol. 2006 Jan;7(1):83-91.
Primary tracheal tumours.
Macchiarini P.
2004 Lancet Oncol. 2004 Feb;5(2):107-18.
Uncommon primary mediastinal tumours.
Macchiarini P, Ostertag H.
2003 Eur J Cardiothorac Surg. 2003 May;23(5):776-81; discussion 781.
Technical advances of pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension.
Hagl C, Khaladj N, Peters T, Hoeper MM, Logemann F, Haverich A, Macchiarini P.
2002 Surg Technol Int. 2002 Sep;10:178-85
Human heart, lung and heart-lung transplantation. Schröder C, Macchiarini P.

Department of Thoracic and Vascular Surgery, Heidehaus Hospital, Hannover MedicalSchool, Hannover, Germany.

2002 Eur J Cardiothorac Surg. 2002 Jul;22(1):41-6.
Technique and results of hyperthermic (41 degrees C) isolated lung perfusion with high-doses of cisplatin for the treatment of surgically relapsing or unresectable lung sarcoma metastasis.
Schröder C, Fisher S, Pieck AC, Müller A, Jaehde U, Kirchner H, Haverich A, Macchiarini P.
2000 Eur J Cardiothorac Surg. 2000 Nov;18(5):513-8
Factors affecting long-term survival after en-bloc resection of lung cancer invading the chest wall.

Chapelier A, Fadel E, Macchiarini P, Lenot B, Le Roy Ladurie F, Cerrina J, Dartevelle P.

1990 Tissue engineered human tracheas for in vivo implantation
Silvia Baiguera (a) , Phillip Jungebluth (a), Alan Burns (b) , Carmelo Mavilia (c) , Johannes Haag (a) , Paolo De Coppi(d) and Paolo Macchiarini(a),
a - BIOAIR Lab, Department of General Thoracic and Regenerative Surgery and Intrathoracic Biotransplantation University Hospital Careggi, Largo Brambilla 3, I-50134 Florence, Italy
b - Neural Development Unit, UCL Institute of Child Health, London, UK
c - Department of Internal Medicine, University of Florence, Via della Pergola 60, I-50121 Florence, Italy
d - Surgery Unit, UCL Institute of Child Health and Great Ormond Street Hospital, London, UK Received 23 July 2010; accepted 4 August 2010. Available online 25 August 2010.
Paolo Macchiarini